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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b82d411d2c3a794dc27ba2d6b653b56b896c7225d4709df57eeb18614864c1d2' 
  AND token = 'QHxsecBPwa7gcADIotKG1iHZ1A/M81NZBw2j29SOlQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}