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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c2ef4a3851046ec3e99b539b5313353fc99b1a09b6484a7cc5fb337628b94bb' 
  AND token = 'VvW2aEEBVZZ7JoZ03U/pZ/a6aABgvc1KxcibG8rrIpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}