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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '340a76fe9e4b77cff10d615bea641d0d81c142b0ea2a411f48ab781f02f0a108' 
  AND token = 'ZtakhtS3FHpQVagBS7adxKsqf1oVlJ7fvvGI018OP6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}