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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78fe9e08e089f41acbd2c63ee25c4b2cc0ebad2be6dbeafe5b1f3fc119a1b0e' 
  AND token = 'fmTSQ2hOfQZ+3ZlujOt9Ay80ef1SINaZ6ENwFmDRYZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}