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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066bfb5a48f77e3e46981f23272d61a08a6e0916a500c982742448b6c2ac3fd1' 
  AND token = '2xhqMDhSaB0NxagqS2gXjURoLfUSLPWspy4uB1yeBkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}