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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b447d5647b9f0e5a1b610b6bcfd8c8800e33509243b5f35d7c0ca7d81c9c084d' 
  AND token = 'NWC1/fBkus7q3MEk5Jojrk0SXQvYh8+b6ayx5c1mrkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}