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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45065a55172d8679176f26503983e0ca8e66d000e5cbdd7e01bdf89e2392e9e' 
  AND token = 'MqimUxeWQRDesCpqSMwP8+y3bQHBHd4+E/2U6DfTcfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}