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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41268c4226c46768fbe48afe5a19314ef174e94fbf49704723f67a360e2d18d' 
  AND token = 'RC5z8ElaxG4IFkhFugYIiNK9qmyZsf6fNI6r4C85ee8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}