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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e1768c372a26c0b2fb7456645aca251a9d4383708c8f9ac3871195448aa6d03' 
  AND token = 'e8fWLi0uOZBBdeWw7L76EcH+aAEoTlT/2ZCPYiM+Zsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}