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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ecf38e24ae115fe77a4c68036114eba5bda6dddb3fa69491f6a0779c246fb6d' 
  AND token = 'M8YNJwr161N4bSs9+G6mwdhB4u9jXh5Y4VPr5u1WB6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}