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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6fdddc49336e6e1a8aabe66141fdd6884cc2e8a9e14bb7f8061f650e62bc28' 
  AND token = '7SXWILiohpLhCSSnSdSXvcsXH1vz5yT3HTIpqS0Z28I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}