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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddb73f99a8532c6a84b8efe2ff075feea28aeaed51f50568d9b2f3c8bab8d0e' 
  AND token = '5GaP96wnPdySohS9Rwi2sLATvgRg/VF+2JHtAhB+msU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}