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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec6bc6064e0fa4a246961d07a11b1a0baf5c65ff93a667000f404492c412816' 
  AND token = 'B94Ay5DjQI0a+VnfxR1tScT0r6U1AiX4YKS4V6p1TUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}