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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2abbea3daff5d924f4c3363e6d4215de2c69648e6ea240ded74c056e070bc7a5' 
  AND token = 'girP6hDWBCNbdD4HBHowhpKPL8ACdiAJog4nMyxyeqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}