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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9683c15a2e3f610f7ca0ffec43156bb03f38bf9f5bb59a73ea2449d3684a4e3' 
  AND token = 'tx7H9crhelUXSAOI+Z67kfRZ8B0OHNDYpgOZGcVa5/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}