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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb2e212a959a43b80c54bf78d8d7d339212b01c4f67b857f144943e8d3df2e1' 
  AND token = '+yYmCWhuTwJkO47umItxa/48Ur9epTa1ItddzbK06nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}