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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6adc8094db0e72bef26d673057f488268c524f357361c2e02fb3797a0c759b9' 
  AND token = 'DMm5GwdzzzkWUYxAbkV4yCnz33C2m5dvUH4a76GUwQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}