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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f85d79513e74d4cca6b54ed7e79499930b8b531991572b4a8cb20a7d34f4c9' 
  AND token = 'Shgz7GLJyuA6IS08SUwj33n3bzFE5uEdkm1fTO3NwFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}