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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a7e8bccd0e352661b705b87e7427ec21a36a989d36b2291515ba694ab37148' 
  AND token = '6d/ujTvglf2jsa4UvXyYfOM0R2QjAXCjfLknJMlrfes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}