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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d9161fe8134819358eb2c08733914501a6d135656d7cd6a12a0a2f482f881a' 
  AND token = '3oXvt9G5Ex55dK1TXn9Fs8dREJlLih4SUx6wEWjEKKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}