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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afeed1fc40b9d0adfceb7a63661d0b31340e2e1c4fd81ff7951676e9c10f5207' 
  AND token = '9H3f78zj5RX3dhmduug8cVSxWGGxJYCGeLLvOCxBwuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}