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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b465d1983a6578da1a672d807ddfa9d0049572e800c6837606e08c146125259f' 
  AND token = 'n1Fa8B3ZSpqzUXUFYvKs0GRiVUaUUW3EvRoSTXXPhpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}