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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f2eeec0111778dc92a240d7291001281e00ae053e30d9ff60c9aca7dc4e572' 
  AND token = 'EG2Pi2bZIqDWysG6JhPidpzoUr6Y+r79hTdbUdyWcU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}