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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1f069149176cb14b6a1a411fa741a1492921b9601132fd1bac662be44b018a' 
  AND token = 'frI8RJ9+hPRMRjJmb9KMz/NvYcSf4KhOK4Gbh2o/ADw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}