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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b29ef7f363b84e16269ed408b34135735e7bb0c2489a090d7691f66f052b6b0' 
  AND token = 'ZsyS+GvuEBfkW+hjkxF6AWAFabC7KXccEYBtPecKlzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}