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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa072854c17fad2927e8a3e76136d72ed1312c222bbbafa6f72f62ea4f4aaf0' 
  AND token = 'Thwupo00RQozalFtjTxSHwqtA4mRrzNNr3+ZEaPSZow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}