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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f43d3490cceb93de9668763bc7f2852d56f99b69ebc503959ff1b6f6957dc2f' 
  AND token = 'wz6yu3C90S0GS/JXwHRcCBPN+8+x/ioCQnLEhD/2/a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}