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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f3ec7b8d72051766f9aed94219aa8d784b1ff43a4451e5e9c347a6adde0576' 
  AND token = 'i7+QNM9iMq2eo2Nbpcua8Y89/LYzHwU7uTHm02lDjbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}