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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1541edc08cd18daf9b3f8ffe8af97f23d7985718e13bf1df932c0313a6d0871c' 
  AND token = 'Imgyau+wZidbveRFa/h/l1sYcQTX4I8JEpqg+Iwu6Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}