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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246b499056005b56f05fa6aaa8a2c9f48f12d8917aaea609bcfd13ea4ba2ea3e' 
  AND token = 'tPovtZIKzt7YhpUWacbm8pAb58D20GAi+pUnMhxWuFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}