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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c063bb6380548ad66dab1033da12dc5d6f75291fd259dcf9759243825f278b' 
  AND token = 'BlARWUoJD/22zRHDNe/9VRVWmHwqd5BVvEJmN1a9p2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}