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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '508e590a678fbcfb55f8804c7e12c450db777042b4166a1fb07df833cac8cda9' 
  AND token = 'mhtSzrDycn1+SAelQH+7j0n7vIgdsSaiXgFeH8S04BQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}