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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69449ad25ace32fdee197db233ec261f29fb4ccc6d902b87d8b2d9a2ec434e9e' 
  AND token = '4boLTx9pE9X2I1gW7wxxqbGsM3iXFpXhiCDUQT5cWCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}