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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e4f607933d77d0f9b9b4b9f97bf537471bd2ec5ced739f5d2196766ee395f1' 
  AND token = 'sud3tUuEV5Yiy20qAVAbDjRgNeICbVLW/y6Nyyj4XHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}