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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aba6c8bfc9913a82d112efbd88a5a398df750819ef57e1d4e8114fe9a77651c' 
  AND token = 'LXwD+H6e2R8/Y0PqicewXhaCBGz3xUPkdFhBpz9dUQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}