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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69e1f121ca27f451cd9d70dfea81d286e0be5eb70ba94f4952425ed1e76e959c' 
  AND token = 'XdCUE+uDtBC9Pw/fSsCXyHP3mB3/xawN1U2v94Q/ahM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}