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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db0b3359ed7a28954248d208f1fa6c8879ded6f45b05a7fb7bbbb14f209bd626' 
  AND token = '8wz2c3y3t7mwXFozIU+0/bdoIDAfYFcRLbSoslRh3uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}