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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '30c78f8dd699a629ebdf1b80481e3372844e01f7e4f341255ed692323a9abbbd' 
  AND token = 'JMG0vWPVC9aUNqHXGMchMMtl24qSWAHb/KrfHsqcqOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}