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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45b6e49573bfcf14696f8ce3b4e93fd87de6df483906b2145dcba058a9e2a89' 
  AND token = 'OPwVHNrQB0xuR0Jp01C5miqS5kQWNJwTQO84wWo2Pvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}