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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8820f9b8a2378f51003f08a2a4a32326f0b92ab043c7b1802f00a10e840065e7' 
  AND token = 'tRLbq61tG5qZtFM/eMEgGEh9R9yXX5sTHe/4uQ2YRqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}