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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f237ed24a49bc3f51cf5595030e535b0cd39ccb9a8bd8741b51d6d326bc729' 
  AND token = 'yNSGPs8gb2TS/wRFYd9ZhPws58Y0+KZtliwRHAnSnXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}