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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f3e3b0cedbee4746ba9eff9d20c3984946aab71d5e4610cdb44af040c64d28' 
  AND token = 'VWR+e8dO/TJLUle8CTOhAt5NWGuPWEcaCVgAoc0LxBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}