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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1f65aa59efc2e8de1d23f91a5b14117dfd778af9f6c6e02d24deb5ba95b82f0' 
  AND token = '+TKGpYZdA/IzINYTmioHk8eIctY9AqCOaeLj/NyvCWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}