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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b03a01127632c9b7ed8101aaf3ef5b0e7873f73b1092719165ee2b84c69e0eac' 
  AND token = 'yOqcfDqGkKWLPS7zeCE/NhB5Xhamg/WKDF1AFR0DWzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}