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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67728f094be35d8af5d218e0f9df565e150cc781e5f445c52a316ed355e8615b' 
  AND token = 'lyL2Iv+zUAkos+2bSfCUIXla25sQoimiNAh92l8aQEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}