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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58c8a2482bfc299022a2eb458ef36cfad26ab0b769aa393db1aa453133979d7b' 
  AND token = 'hux2GfCvc+X2luTp6WsCbdUryP1+1S0lR4BLG203zwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}