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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd3b770ad4c334fc9e383f60c8e84a94fc2af08bbf66d7d2a0abf7e9af16668' 
  AND token = 'XrqCKBYRnhmRywA85veUxzcSXBSEPAY8s9jPyXsTmGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}