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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8f26021db241b3229c7adcf4b16c3684941a73b52258817dc5befdf2e3382a7' 
  AND token = 'bQlHyWSYV7gw4fki5BCR0Nnj8eg624donHnPnaiDT3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}