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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c74a09b7e22aac7adb2c42f760602900cd8aa31ed67eb44e696a8afb1b34c4c4' 
  AND token = 'N+/G2O0MJOkLAG3K4voB8SXMQRDyjYIaZoSZvL1v6Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}