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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e68c111aaa0bb13d0a1065a13177d54dd6412a40018db4f7b5e1dea3de8366b0' 
  AND token = 'C7nyTa/Qxe+Jo8N2BiKQ11h3RY52RHBbVKfW3QLWt2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}